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Universiteit Leiden

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2008

Geldof, M., Freijer, J. I, Peletier, L.A., van Beijsterveldt, L., Danhof, M. , Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex, Eur J Pharm Sci, vol. 33, no. 3, pp. 217-29.

Huntjens, D.R., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D.J., Danhof, M., Della Pasqua, O. , Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats, Br J Pharmacol, vol. 153, no. 5, pp. 1072-84.

2007

Geldof, M., Freijer, J., van Beijsterveldt, L., Timmerman, P., Ahnaou, A., Drinkenburg, W.H., Danhof, M. , Population pharmacokinetic model of fluvoxamine in rats: utility for application in animal behavioral studies, Eur J Pharm Sci, vol. 30, no. 1, pp. 45-55.

2006

Huntjens, D.R., Spalding, D.J., Danhof, M., Della Pasqua, O.E. , Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers, Br J Pharmacol, vol. 148, no. 4, pp. 396-404.

van Dorp, E., Yassen, A., Sarton, E., Romberg, R., Olofsen, E., Teppema, L., Danhof, M., Dahan, A. , Naloxone reversal of buprenorphine-induced respiratory depression, Anesthesiology, vol. 105, no. 1, pp. 51-7.

2005

Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., Boellaard, R., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo by positron emission tomography, Mol Imaging Biol, vol. 7, no. 6, pp. 411-21.

Huntjens, D.R., Danhof, M., Della Pasqua, O.E. , Pharmacokinetic-pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors, Rheumatology (Oxford), vol. 44, no. 7, pp. 846-59.

Schaddelee, M.P., Read, K.D., Cleypool, C.G., Ijzerman, A.P., Danhof, M., de Boer, A.G. , Brain penetration of synthetic adenosine A1 receptor agonists in situ: role of the rENT1 nucleoside transporter and binding to blood constituents, Eur J Pharm Sci, vol. 24, no. 1, pp. 59-66.

2003

Bueters, T.J., van Duivenvoorde, L.M., Danhof, M., AP, I.J., van Helden, H.P. , Cyclopentyladenosine and some of its low-efficacy derivatives inhibit striatal synaptosomal release of acetylcholine to a similar degree, Eur J Pharmacol, vol. 481, no. 2-3, pp. 141-6.

Bueters, T.J., Joosen, M.J., van Helden, H.P., Ijzerman, A.P., Danhof, M. , Adenosine A1 receptor agonist N6-cyclopentyladenosine affects the inactivation of acetylcholinesterase in blood and brain by sarin, J Pharmacol Exp Ther, vol. 304, no. 3, pp. 1307-13.

2002

Bueters, T.J., Groen, B., Danhof, M., AP, I.J., Van Helden, H.P. , Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication, Arch Toxicol, vol. 76, no. 11, pp. 650-6.

Zuideveld, K.P., Treijtel, N., Maas, H.J., Gubbens-Stibbe, J.M., Peletier, L.A., van Der Graaf, P.H., Danhof, M. , A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia, J Pharmacol Exp Ther, vol. 300, no. 1, pp. 330-8.

2000

Cleton, A., Altorf, B.A., Voskuyl, R.A., Danhof, M. , Effect of amygdala kindling on the central nervous system effects of tiagabine: EEG effects versus brain GABA levels, Br J Pharmacol, vol. 130, no. 5, pp. 1037-44.

1999

Cleton, A., de Greef, H.J., Edelbroek, P.M., Voskuyl, R.A., Danhof, M. , Application of a combined "effect compartment/indirect response model" to the central nervous system effects of tiagabine in the rat, J Pharmacokinet Biopharm, vol. 27, no. 3, pp. 301-23.

1998

Snoeck, E., Ver Donck, K., Jacqmin, P., Van Belle, H., Dupont, A.G., Van Peer, A., Danhof, M. , Physiological red blood cell kinetic model to explain the apparent discrepancy between adenosine breakdown inhibition and nucleoside transporter occupancy of draflazine, J Pharmacol Exp Ther, vol. 286, no. 1, pp. 142-9.

1997

Snoeck, E., Piotrovskij, V., Jacqmin, P., Lins, R.L., Van Peer, A., Danhof, M., Woestenborghs, R., Van Gool, R., Dupont, A.G., Heykants, J. , Population analysis of the non-linear red blood cell partitioning of draflazine following various infusion durations, Eur J Clin Pharmacol, vol. 53, no. 1, pp. 57-63.

1996

Snoeck, E., Jacqmin, P., Van Peer, A., Danhof, M., Ver Donck, K., Van Belle, H., Woestenborghs, R., Crabbe, R., Van Gool, R., Dupont, A., Heykants, J. , The implications of non-linear red blood cell partitioning for the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor draflazine, Br J Clin Pharmacol, vol. 42, no. 5, pp. 605-13.

Mathoot, R.A., Soudijn, W., Breimer, D.D., Ijzerman, A.P., Danhof, M. , Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A1 and A2a receptors in vivo, Br J Pharmacol, vol. 118, no. 2, pp. 369-77.

1992

Mandema, J.W., Tukker, E., Danhof, M. , In vivo characterization of the pharmacodynamic interaction of a benzodiazepine agonist and antagonist: midazolam and flumazenil, J Pharmacol Exp Ther, vol. 260, no. 1, pp. 36-44.

Danhof, M., de Boer, A., Magnani, H.N., Stiekema, J.C. , Pharmacokinetic considerations on Orgaran (Org 10172) therapy, Haemostasis, vol. 22, no. 2, pp. 73-84.

1991

de Boer, A., Danhof, M., Cohen, A.F., Magnani, H.N., Breimer, D.D. , Interaction study between Org 10172, a low molecular weight heparinoid, and acetylsalicylic acid in healthy male volunteers, Thromb Haemost, vol. 66, no. 2, pp. 202-7.

Mandema, J.W., Sansom, L.N., Dios-Vieitez, M.C., Hollander-Jansen, M., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the electroencephalographic effects of benzodiazepines. Correlation with receptor binding and anticonvulsant activity, J Pharmacol Exp Ther, vol. 257, no. 1, pp. 472-8.

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