LACDR

Universiteit Leiden

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2007

Danhof, M., de Jongh, J., De Lange, E.C., Della Pasqua, O., Ploeger, B.A., Voskuyl, R.A. , Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis, Annu Rev Pharmacol Toxicol, vol. 47, pp. 357-400.

2002

de Lange, E.C., Danhof, M. , Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain, Clin Pharmacokinet, vol. 41, no. 10, pp. 691-703.

1997

de Lange, E.C., Danhof, M., de Boer, A.G., Breimer, D.D. , Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier, Brain Res Brain Res Rev, vol. 25, no. 1, pp. 27-49.

1992

Stijnen, A.M., Danhof, M., Van Bezooijen, C.F. , Increased sensitivity to the anesthetic effect of phenobarbital in aging BN/BiRij rats, J Pharmacol Exp Ther, vol. 261, no. 1, pp. 81-7.

Mandema, J.W., Heijligers-Feijen, C.D., Tukker, E., De Boer, A.G., Danhof, M. , Modeling of the effect site equilibration kinetics and pharmacodynamics of racemic baclofen and its enantiomers using quantitative EEG effect measures, J Pharmacol Exp Ther, vol. 261, no. 1, pp. 88-95.

LACDR