LACDR

Universiteit Leiden

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2008

Groenendaal, D., Freijer, J., Rosier, A., de Mik, D., Nicholls, G., Hersey, A., Ayrton, A.D., Danhof, M., de Lange, E.C. , Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci, vol. 34, no. 2-3, pp. 149-63.

Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78.

Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effectiveness and safety of buprenorphine and fentanyl in rats, Pharm Res, vol. 25, no. 1, pp. 183-93.

Maas, H.J., Snelder, N., Danhof, M., Della Pasqua, O. , Prediction of attack frequency in migraine treatment, Cephalalgia, vol. 28, no. 8, pp. 847-55.

Post, T.M., Freijer, J. I, Ploeger, B.A., Danhof, M. , Extensions to the visual predictive check to facilitate model performance evaluation, J Pharmacokinet Pharmacodyn, vol. 35, no. 2, pp. 185-202.

2007

Groenendaal, D., Freijer, J., de Mik, D., Bouw, M.R., Danhof, M., de Lange, E.C. , Influence of biophase distribution and P-glycoprotein interaction on pharmacokinetic-pharmacodynamic modelling of the effects of morphine on the EEG, Br J Pharmacol, vol. 151, no. 5, pp. 713-20.

2002

Visser, S.A., Smulders, C.J., Reijers, B.P., Van der Graaf, P.H., Peletier, L.A., Danhof, M. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of concentration-dependent hysteresis and biphasic electroencephalogram effects of alphaxalone in rats, J Pharmacol Exp Ther, vol. 302, no. 3, pp. 1158-67.

1998

Cox, E.H., Knibbe, C.A., Koster, V.S., Langemeijer, M.W., Tukker, E.E., Lange, R., Kuks, P.F., Langemeijer, H.J., Lie, A.H.L., Danhof, M. , Influence of different fat emulsion-based intravenous formulations on the pharmacokinetics and pharmacodynamics of propofol, Pharm Res, vol. 15, no. 3, pp. 442-8.

1988

Koopmans, R., Dingemanse, J., Danhof, M., Horsten, G.P., van Boxtel, C.J. , Pharmacokinetic-pharmacodynamic modeling of midazolam effects on the human central nervous system, Clin Pharmacol Ther, vol. 44, no. 1, pp. 14-22.

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