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Universiteit Leiden

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2008

Santen, G., Danhof, M., Della Pasqua, O. , Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model, J Psychiatr Res, vol. 42, no. 14, pp. 1189-97.

Santen, G., Gomeni, R., Danhof, M., Della Pasqua, O. , Sensitivity of the individual items of the Hamilton depression rating scale to response and its consequences for the assessment of efficacy, J Psychiatr Res, vol. 42, no. 12, pp. 1000-9.

Geldof, M., Freijer, J. I, Peletier, L.A., van Beijsterveldt, L., Danhof, M. , Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex, Eur J Pharm Sci, vol. 33, no. 3, pp. 217-29.

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther, vol. 324, no. 3, pp. 1234-42.

Huntjens, D.R., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D.J., Danhof, M., Della Pasqua, O. , Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats, Br J Pharmacol, vol. 153, no. 5, pp. 1072-84.

Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78.

Muller, A.E., DeJongh, J., Oostvogel, P.M., Voskuyl, R.A., Dorr, P.J., Danhof, M., Mouton, J.W. , Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6.

Clinckers, R., Smolders, I, Michotte, Y., Ebinger, G., Danhof, M., Voskuyl, R.A., Della Pasqua, O. , Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain, Br J Pharmacol, vol. 155, no. 7, pp. 1127-38.

Muller, A.E., Dorr, P.J., Mouton, J.W., De Jongh, J., Oostvogel, P.M., Steegers, E.A., Voskuyl, R.A., Danhof, M. , The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women, Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74.

Maas, H.J., Snelder, N., Danhof, M., Della Pasqua, O. , Prediction of attack frequency in migraine treatment, Cephalalgia, vol. 28, no. 8, pp. 847-55.

Geldof, M., Freijer, J., van Beijsterveldt, L., Danhof, M. , Pharmacokinetic modeling of non-linear brain distribution of fluvoxamine in the rat, Pharm Res, vol. 25, no. 4, pp. 792-804.

Maas, H.J., Spruit, M.A., Danhof, M., Della Pasqua, O.E. , Relevance of absorption rate and lag time to the onset of action in migraine, Clin Pharmacokinet, vol. 47, no. 2, pp. 139-46.

2007

Muller, A.E., DeJongh, J., Bult, Y., Goessens, W.H., Mouton, J.W., Danhof, M., van den Anker, J.N. , Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks, Antimicrob Agents Chemother, vol. 51, no. 10, pp. 3720-5.

Zuideveld, K.P., Van der Graaf, P.H., Peletier, L.A., Danhof, M. , Allometric scaling of pharmacodynamic responses: application to 5-Ht1A receptor mediated responses from rat to man, Pharm Res, vol. 24, no. 11, pp. 2031-9.

Geldof, M., Freijer, J., van Beijsterveldt, L., Vermote, P.C., Megens, A.A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine on p-chloroamphetamine-induced behavior, Eur J Pharm Sci, vol. 32, no. 3, pp. 200-8.

Yassen, A., Kan, J., Olofsen, E., Suidgeest, E., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of norbuprenorphine in rats, J Pharmacol Exp Ther, vol. 321, no. 2, pp. 598-607.

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint, Br J Pharmacol, vol. 151, no. 3, pp. 356-66.

van Steeg, T.J., Krekels, E.H., Danhof, M., de Lange, E.C. , Reproducible and time-dependent modification of serum protein binding in Wistar Kyoto rats, J Pharmacol Toxicol Methods, vol. 56, no. 1, pp. 72-8.

Freijer, J. I, Post, T.M., Ploeger, B.A., DeJongh, J., Danhof, M. , Application of the convection-dispersion equation to modelling oral drug absorption, Bull Math Biol, vol. 69, no. 1, pp. 181-95.

Yassen, A., Olofsen, E., Romberg, R., Sarton, E., Teppema, L., Danhof, M., Dahan, A. , Mechanism-based PK/PD modeling of the respiratory depressant effect of buprenorphine and fentanyl in healthy volunteers, Clin Pharmacol Ther, vol. 81, no. 1, pp. 50-8.

Geldof, M., Freijer, J., van Beijsterveldt, L., Timmerman, P., Ahnaou, A., Drinkenburg, W.H., Danhof, M. , Population pharmacokinetic model of fluvoxamine in rats: utility for application in animal behavioral studies, Eur J Pharm Sci, vol. 30, no. 1, pp. 45-55.

Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine, Clin Pharmacokinet, vol. 46, no. 5, pp. 433-47.

Yassen, A., Olofsen, E., van Dorp, E., Sarton, E., Teppema, L., Danhof, M., Dahan, A. , Mechanism-based pharmacokinetic-pharmacodynamic modelling of the reversal of buprenorphine-induced respiratory depression by naloxone : a study in healthy volunteers, Clin Pharmacokinet, vol. 46, no. 11, pp. 965-80.

2006

Maas, H.J., Danhof, M., Della Pasqua, O. , A model-based approach to treatment comparison in acute migraine, Br J Clin Pharmacol, vol. 62, no. 5, pp. 591-600.

Yassen, A., Kan, J., Olofsen, E., Suidgeest, E., Dahan, A., Danhof, M. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of the respiratory-depressant effect of buprenorphine and fentanyl in rats, J Pharmacol Exp Ther, vol. 319, no. 2, pp. 682-92.

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