LACDR

Universiteit Leiden

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2008

Groenendaal, D., Freijer, J., Rosier, A., de Mik, D., Nicholls, G., Hersey, A., Ayrton, A.D., Danhof, M., de Lange, E.C. , Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci, vol. 34, no. 2-3, pp. 149-63.

Geldof, M., Freijer, J., van Beijsterveldt, L., Danhof, M. , Pharmacokinetic modeling of non-linear brain distribution of fluvoxamine in the rat, Pharm Res, vol. 25, no. 4, pp. 792-804.

2005

Schaddelee, M.P., Read, K.D., Cleypool, C.G., Ijzerman, A.P., Danhof, M., de Boer, A.G. , Brain penetration of synthetic adenosine A1 receptor agonists in situ: role of the rENT1 nucleoside transporter and binding to blood constituents, Eur J Pharm Sci, vol. 24, no. 1, pp. 59-66.

2004

Visser, C.C., Stevanovic, S., Heleen Voorwinden, L., Gaillard, P.J., Crommelin, D.J., Danhof, M., De Boer, A.G. , Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro, J Drug Target, vol. 12, no. 3, pp. 145-50.

2003

Schaddelee, M.P., Voorwinden, H.L., van Tilburg, E.W., Pateman, T.J., Ijzerman, A.P., Danhof, M., de Boer, A.G. , Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: possible implications for the design of synthetic adenosine derivatives, Eur J Pharm Sci, vol. 19, no. 1, pp. 13-22.

1995

de Lange, E.C., Danhof, M., Zurcher, C., de Boer, A.G., Breimer, D.D. , Repeated microdialysis perfusions: periprobe tissue reactions and BBB permeability, Brain Res, vol. 702, no. 1-2, pp. 261-5.

1993

Van Bree, J.B., De Boer, A.G., Danhof, M., Breimer, D.D. , Drug transport across the blood-brain barrier. III. Mechanisms and methods to improve drug delivery to the central nervous system, Pharm World Sci, vol. 15, no. 1, pp. 2-9.

1989

van Bree, J.B., de Boer, A.G., Verhoef, J.C., Danhof, M., Breimer, D.D. , Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells, J Pharmacol Exp Ther, vol. 249, no. 3, pp. 901-5.

1988

van Bree, J.B., de Boer, A.G., Danhof, M., Ginsel, L.A., Breimer, D.D. , Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs, J Pharmacol Exp Ther, vol. 247, no. 3, pp. 1233-9.

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