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Universiteit Leiden

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2008

Huntjens, D.R., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D.J., Danhof, M., Della Pasqua, O. , Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats, Br J Pharmacol, vol. 153, no. 5, pp. 1072-84.

Maas, H.J., Spruit, M.A., Danhof, M., Della Pasqua, O.E. , Relevance of absorption rate and lag time to the onset of action in migraine, Clin Pharmacokinet, vol. 47, no. 2, pp. 139-46.

2007

Liefaard, L.C., Gunput, R.A., Danhof, M., Voskuyl, R.A. , Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy, Epilepsia, vol. 48, no. 7, pp. 1378-87.

Freijer, J. I, Post, T.M., Ploeger, B.A., DeJongh, J., Danhof, M. , Application of the convection-dispersion equation to modelling oral drug absorption, Bull Math Biol, vol. 69, no. 1, pp. 181-95.

1992

Mandema, J.W., Tuk, B., van Steveninck, A.L., Breimer, D.D., Cohen, A.F., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers, Clin Pharmacol Ther, vol. 51, no. 6, pp. 715-28.

1991

Mandema, J.W., Tukker, E., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of the EEG effects of midazolam in individual rats: influence of rate and route of administration, Br J Pharmacol, vol. 102, no. 3, pp. 663-8.

De Boer, A., Stiekema, J.C., Danhof, M., Breimer, D.D. , The influence of Org 10172, a low molecular weight heparinoid, on antipyrine metabolism and the effect of enzyme induction on the response to Org 10172, Br J Clin Pharmacol, vol. 32, no. 1, pp. 23-9.

Koopmans, R., Dingemanse, J., Danhof, M., Horsten, G.P., van Boxtel, C.J. , The influence of dosage time of midazolam on its pharmacokinetics and effects in humans, Clin Pharmacol Ther, vol. 50, no. 1, pp. 16-24.

de Boer, A., Stiekema, J.C., Danhof, M., Moolenaar, A.J., Breimer, D.D. , Interaction of ORG 10172, a low molecular weight heparinoid, and digoxin in healthy volunteers, Eur J Clin Pharmacol, vol. 41, no. 3, pp. 245-50.

Mandema, J.W., Gubbens-Stibbe, J.M., Danhof, M. , Stability and pharmacokinetics of flumazenil in the rat, Psychopharmacology (Berl), vol. 103, no. 3, pp. 384-7.

1989

van Harten, J., Burggraaf, J., Danhof, M., van Brummelen, P., Breimer, D.D. , The contribution of nisoldipine-induced changes in liver blood flow to its pharmacokinetics after oral administration, Br J Clin Pharmacol, vol. 27, no. 5, pp. 581-6.

van Harten, J., van Brummelen, P., Ooms, P., Danhof, M., Blauw, G.J., Breimer, D.D. , Variability in the pharmacokinetics of nisoldipine as caused by differences in liver blood flow response, J Clin Pharmacol, vol. 29, no. 8, pp. 714-21.

van Harten, J., van Brummelen, P., Danhof, M., Quekel, R.P., Breimer, D.D. , Pharmacokinetics and hemodynamic effects of long-term nisoldipine treatment in hypertensive patients, J Cardiovasc Pharmacol, vol. 13, no. 4, pp. 624-9.

1988

Schellens, J.H., van der Wart, J.H., Danhof, M., van der Velde, E.A., Breimer, D.D. , Relationship between the metabolism of antipyrine, hexobarbitone and theophylline in man as assessed by a 'cocktail' approach, Br J Clin Pharmacol, vol. 26, no. 4, pp. 373-84.

van Harten, J., van Brummelen, P., Lodewijks, M.T., Danhof, M., Breimer, D.D. , Pharmacokinetics and hemodynamic effects of nisoldipine and its interaction with cimetidine, Clin Pharmacol Ther, vol. 43, no. 3, pp. 332-41.

1987

van Harten, J., Burggraaf, K., Danhof, M., van Brummelen, P., Breimer, D.D. , Negligible sublingual absorption of nifedipine, Lancet, vol. 2, no. 8572, pp. 1363-5.

1986

Kleinbloesem, C.H., van Harten, J., Wilson, J.P., Danhof, M., van Brummelen, P., Breimer, D.D. , Nifedipine: kinetics and hemodynamic effects in patients with liver cirrhosis after intravenous and oral administration, Clin Pharmacol Ther, vol. 40, no. 1, pp. 21-8.

1985

Kleinbloesem, C.H., van Brummelen, P., van Harten, J., Danhof, M., Breimer, D.D. , Nifedipine: influence of renal function on pharmacokinetic/hemodynamic relationship, Clin Pharmacol Ther, vol. 37, no. 5, pp. 563-74.

1982

Danhof, M., Teunissen, M.W., Breimer, D.D. , 3-Hydroxymethyl antipyrine excretion in urine after an oral dose of antipyrine. A reconsideration of previously published data and synthesis of a pure reference substance, Pharmacology, vol. 24, no. 3, pp. 181-4.

Danhof, M., van Zuilen, A., Boeijinga, J.K., Breimer, D.D. , Studies of the different metabolic pathways of antipyrine in man. Oral versus i.v. administration and the influence of urinary collection time, Eur J Clin Pharmacol, vol. 21, no. 5, pp. 433-41.

1979

Danhof, M., Breimer, D.D. , Studies on the different metabolic pathways of antipyrine in man. I. Oral administration of 250, 500 and 1000 mg to healthy volunteers, Br J Clin Pharmacol, vol. 8, no. 6, pp. 529-37.

Danhof, M., de Boer, A.G., de der Groot-van Vis, E., Breimer, D.D. , Assay of 3-carboxy-antipyrine in urine by capillary gas chromatography with nitrogen selective detection. Some preliminary results in man, Pharmacology, vol. 19, no. 4, pp. 215-20.

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