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Universiteit Leiden

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2008

Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78.

2007

Groenendaal, D., Freijer, J., de Mik, D., Bouw, M.R., Danhof, M., de Lange, E.C. , Influence of biophase distribution and P-glycoprotein interaction on pharmacokinetic-pharmacodynamic modelling of the effects of morphine on the EEG, Br J Pharmacol, vol. 151, no. 5, pp. 713-20.

2006

Nugroho, A.K., Romeijn, S.G., Zwier, R., de Vries, J.B., Dijkstra, D., Wikstrom, H., Della-Pasqua, O., Danhof, M., Bouwstra, J.A. , Pharmacokinetics and pharmacodynamics analysis of transdermal iontophoresis of 5-OH-DPAT in rats: in vitro-in vivo correlation, J Pharm Sci, vol. 95, no. 7, pp. 1570-85.

2005

Groenendaal, D., Blom-Roosemalen, M.C., Danhof, M., Lange, E.C. , High-performance liquid chromatography of nalbuphine, butorphanol and morphine in blood and brain microdialysate samples: application to pharmacokinetic/pharmacodynamic studies in rats, J Chromatogr B Analyt Technol Biomed Life Sci, vol. 822, no. 1-2, pp. 230-7.

2004

Schaddelee, M.P., Groenendaal, D., DeJongh, J., Cleypool, C.G., AP, I.J., De Boer, A.G., Danhof, M. , Population pharmacokinetic modeling of blood-brain barrier transport of synthetic adenosine A1 receptor agonists, J Pharmacol Exp Ther, vol. 311, no. 3, pp. 1138-46.

2003

Bueters, T.J., van Helden, H.P., AP, I.J., Danhof, M. , Low efficacy adenosine A1 agonists inhibit striatal acetylcholine release in rats improving central selectivity of action, Neurosci Lett, vol. 343, no. 1, pp. 57-61.

2002

Bueters, T.J., Groen, B., Danhof, M., AP, I.J., Van Helden, H.P. , Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication, Arch Toxicol, vol. 76, no. 11, pp. 650-6.

1997

de Lange, E.C., Danhof, M., de Boer, A.G., Breimer, D.D. , Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier, Brain Res Brain Res Rev, vol. 25, no. 1, pp. 27-49.

1995

de Lange, E.C., Danhof, M., Zurcher, C., de Boer, A.G., Breimer, D.D. , Repeated microdialysis perfusions: periprobe tissue reactions and BBB permeability, Brain Res, vol. 702, no. 1-2, pp. 261-5.

de Lange, E.C., de Vries, J.D., Zurcher, C., Danhof, M., de Boer, A.G., Breimer, D.D. , The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain, Pharm Res, vol. 12, no. 12, pp. 1924-31.

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