LACDR

Universiteit Leiden

List
Filter

Found 243 results. Export: Tagged | XML

Filters: keyword is K [Clear All Filters]

2009

Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., de Jong, H.W., Dijkstra, J., van der Weerd, L., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Changes in GABAA receptor properties in amygdala kindled animals: in vivo studies using [11C]flumazenil and positron emission tomography, Epilepsia, vol. 50, no. 1, pp. 88-98.

Ploeger, B.A., Smeets, J., Strougo, A., Drenth, H.J., Ruigt, G., Houwing, N., Danhof, M. , Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex, Anesthesiology, vol. 110, no. 1, pp. 95-105.

2008

Santen, G., Danhof, M., Della Pasqua, O. , Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model, J Psychiatr Res, vol. 42, no. 14, pp. 1189-97.

Ravenstijn, P.G., Merlini, M., Hameetman, M., Murray, T.K., Ward, M.A., Lewis, H., Ball, G., Mottart, C., de Ville Goyet, C., Lemarchand, T., van Belle, K., O'Neill, M.J., Danhof, M., de Lange, E.C. , The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments, J Pharmacol Toxicol Methods, vol. 57, no. 2, pp. 114-30.

Geldof, M., Freijer, J. I, Peletier, L.A., van Beijsterveldt, L., Danhof, M. , Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex, Eur J Pharm Sci, vol. 33, no. 3, pp. 217-29.

Peeters, M.Y., Bras, L.J., DeJongh, J., Wesselink, R.M., Aarts, L.P., Danhof, M., Knibbe, C.A. , Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients, Clin Pharmacol Ther, vol. 83, no. 3, pp. 443-51.

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther, vol. 324, no. 3, pp. 1234-42.

Huntjens, D.R., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D.J., Danhof, M., Della Pasqua, O. , Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats, Br J Pharmacol, vol. 153, no. 5, pp. 1072-84.

Peeters, M.Y., Aarts, L.P., Boom, F.A., Bras, L.J., Tibboel, D., Danhof, M., Knibbe, C.A. , Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients, Eur J Clin Pharmacol, vol. 64, no. 3, pp. 329-34.

Groenendaal, D., Freijer, J., Rosier, A., de Mik, D., Nicholls, G., Hersey, A., Ayrton, A.D., Danhof, M., de Lange, E.C. , Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci, vol. 34, no. 2-3, pp. 149-63.

Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78.

Muller, A.E., DeJongh, J., Oostvogel, P.M., Voskuyl, R.A., Dorr, P.J., Danhof, M., Mouton, J.W. , Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6.

Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effectiveness and safety of buprenorphine and fentanyl in rats, Pharm Res, vol. 25, no. 1, pp. 183-93.

Clinckers, R., Smolders, I, Michotte, Y., Ebinger, G., Danhof, M., Voskuyl, R.A., Della Pasqua, O. , Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain, Br J Pharmacol, vol. 155, no. 7, pp. 1127-38.

Muller, A.E., Dorr, P.J., Mouton, J.W., De Jongh, J., Oostvogel, P.M., Steegers, E.A., Voskuyl, R.A., Danhof, M. , The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women, Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74.

Post, T.M., Freijer, J. I, Ploeger, B.A., Danhof, M. , Extensions to the visual predictive check to facilitate model performance evaluation, J Pharmacokinet Pharmacodyn, vol. 35, no. 2, pp. 185-202.

Danhof, M., de Lange, E.C., Della Pasqua, O.E., Ploeger, B.A., Voskuyl, R.A. , Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research, Trends Pharmacol Sci, vol. 29, no. 4, pp. 186-91.

Geldof, M., Freijer, J., van Beijsterveldt, L., Danhof, M. , Pharmacokinetic modeling of non-linear brain distribution of fluvoxamine in the rat, Pharm Res, vol. 25, no. 4, pp. 792-804.

Maas, H.J., Spruit, M.A., Danhof, M., Della Pasqua, O.E. , Relevance of absorption rate and lag time to the onset of action in migraine, Clin Pharmacokinet, vol. 47, no. 2, pp. 139-46.

2007

Anisimov, V.V., Maas, H.J., Danhof, M., Della Pasqua, O. , Analysis of responses in migraine modelling using hidden Markov models, Stat Med, vol. 26, no. 22, pp. 4163-78.

Muller, A.E., DeJongh, J., Bult, Y., Goessens, W.H., Mouton, J.W., Danhof, M., van den Anker, J.N. , Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks, Antimicrob Agents Chemother, vol. 51, no. 10, pp. 3720-5.

Zuideveld, K.P., Van der Graaf, P.H., Peletier, L.A., Danhof, M. , Allometric scaling of pharmacodynamic responses: application to 5-Ht1A receptor mediated responses from rat to man, Pharm Res, vol. 24, no. 11, pp. 2031-9.

Geldof, M., Freijer, J., van Beijsterveldt, L., Vermote, P.C., Megens, A.A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine on p-chloroamphetamine-induced behavior, Eur J Pharm Sci, vol. 32, no. 3, pp. 200-8.

Yassen, A., Kan, J., Olofsen, E., Suidgeest, E., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of norbuprenorphine in rats, J Pharmacol Exp Ther, vol. 321, no. 2, pp. 598-607.

Jonker, D.M., Voskuyl, R.A., Danhof, M. , Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments?, Epilepsia, vol. 48, no. 3, pp. 412-34.

LACDR