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Universiteit Leiden

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2008

Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78.

2007

Muller, A.E., DeJongh, J., Bult, Y., Goessens, W.H., Mouton, J.W., Danhof, M., van den Anker, J.N. , Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks, Antimicrob Agents Chemother, vol. 51, no. 10, pp. 3720-5.

Geldof, M., Freijer, J., van Beijsterveldt, L., Vermote, P.C., Megens, A.A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine on p-chloroamphetamine-induced behavior, Eur J Pharm Sci, vol. 32, no. 3, pp. 200-8.

Geldof, M., Freijer, J., van Beijsterveldt, L., Timmerman, P., Ahnaou, A., Drinkenburg, W.H., Danhof, M. , Population pharmacokinetic model of fluvoxamine in rats: utility for application in animal behavioral studies, Eur J Pharm Sci, vol. 30, no. 1, pp. 45-55.

2005

Knibbe, C.A., Zuideveld, K.P., Aarts, L.P., Kuks, P.F., Danhof, M. , Allometric relationships between the pharmacokinetics of propofol in rats, children and adults, Br J Clin Pharmacol, vol. 59, no. 6, pp. 705-11.

2004

Knibbe, C.A., Naber, H., Aarts, L.P., Kuks, P.F., Danhof, M. , Long-term sedation with propofol 60 mg ml(-1) vs. propofol 10 mg(-1) ml in critically ill, mechanically ventilated patients, Acta Anaesthesiol Scand, vol. 48, no. 3, pp. 302-7.

Swart, E.L., Zuideveld, K.P., de Jongh, J., Danhof, M., Thijs, L.G., van Strack Schijndel, R.M. , Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients, Br J Clin Pharmacol, vol. 57, no. 2, pp. 135-45.

Schaddelee, M.P., Groenendaal, D., DeJongh, J., Cleypool, C.G., AP, I.J., De Boer, A.G., Danhof, M. , Population pharmacokinetic modeling of blood-brain barrier transport of synthetic adenosine A1 receptor agonists, J Pharmacol Exp Ther, vol. 311, no. 3, pp. 1138-46.

2002

Knibbe, C.A., Melenhorst-de Jong, G., Mestrom, M., Rademaker, C.M., Reijnvaan, A.F., Zuideveld, K.P., Kuks, P.F., van Vught, H., Danhof, M. , Pharmacokinetics and effects of propofol 6% for short-term sedation in paediatric patients following cardiac surgery, Br J Clin Pharmacol, vol. 54, no. 4, pp. 415-22.

2000

Della Paschoa, O.E., Hoogerkamp, A., Edelbroek, P.M., Voskuyl, R.A., Danhof, M. , Pharmacokinetic-pharmacodynamic correlation of lamotrigine, flunarizine, loreclezole, CGP40116 and CGP39551 in the cortical stimulation model, Epilepsy Res, vol. 40, no. 1, pp. 41-52.

Knibbe, C.A., Aarts, L.P., Kuks, P.F., Voortman, H.J., Lie, A.H.L., Bras, L.J., Danhof, M. , Pharmacokinetics and pharmacodynamics of propofol 6% SAZN versus propofol 1% SAZN and Diprivan-10 for short-term sedation following coronary artery bypass surgery, Eur J Clin Pharmacol, vol. 56, no. 1, pp. 89-95.

1999

Knibbe, C.A., Koster, V.S., Aarts, L.P., Langemeijer, H.J., Danhof, M. , Pilot study in humans on the pharmacokinetics and safety of propofol 6% SAZN, Pharm World Sci, vol. 21, no. 5, pp. 239-40.

Cleton, A., Mazee, D., Voskuyl, R.A., Danhof, M. , Rate of change of blood concentrations is a major determinant of the pharmacodynamics of midazolam in rats, Br J Pharmacol, vol. 127, no. 1, pp. 227-35.

Knibbe, C.A., Voortman, H.J., Aarts, L.P., Kuks, P.F., Lange, R., Langemeijer, H.J., Danhof, M. , Pharmacokinetics, induction of anaesthesia and safety characteristics of propofol 6% SAZN vs propofol 1% SAZN and Diprivan-10 after bolus injection, Br J Clin Pharmacol, vol. 47, no. 6, pp. 653-60.

Cox, E.H., Langemeijer, M.W., Gubbens-Stibbe, J.M., Muir, K.T., Danhof, M. , The comparative pharmacodynamics of remifentanil and its metabolite, GR90291, in a rat electroencephalographic model, Anesthesiology, vol. 90, no. 2, pp. 535-44.

Van der Graaf, P.H., Van Schaick, E.A., Visser, S.A., De Greef, H.J., Ijzerman, A.P., Danhof, M. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: prediction of tissue-dependent efficacy in vivo, J Pharmacol Exp Ther, vol. 290, no. 2, pp. 702-9.

1998

Cleton, A., Voskuyl, R.A., Danhof, M. , Adaptive changes in the pharmacodynamics of midazolam in different experimental models of epilepsy: kindling, cortical stimulation and genetic absence epilepsy, Br J Pharmacol, vol. 125, no. 4, pp. 615-20.

Cox, E.H., Knibbe, C.A., Koster, V.S., Langemeijer, M.W., Tukker, E.E., Lange, R., Kuks, P.F., Langemeijer, H.J., Lie, A.H.L., Danhof, M. , Influence of different fat emulsion-based intravenous formulations on the pharmacokinetics and pharmacodynamics of propofol, Pharm Res, vol. 15, no. 3, pp. 442-8.

1997

van Schaick, E.A., de Greef, H.J., Ijzerman, A.P., Danhof, M. , Physiological indirect effect modeling of the antilipolytic effects of adenosine A1-receptor agonists, J Pharmacokinet Biopharm, vol. 25, no. 6, pp. 673-94.

Snoeck, E., Piotrovskij, V., Jacqmin, P., Lins, R.L., Van Peer, A., Danhof, M., Woestenborghs, R., Van Gool, R., Dupont, A.G., Heykants, J. , Population analysis of the non-linear red blood cell partitioning of draflazine following various infusion durations, Eur J Clin Pharmacol, vol. 53, no. 1, pp. 57-63.

1996

Danhof, M. , Applications of pharmacokinetic/pharmacodynamic research in rational drug development, Methods Find Exp Clin Pharmacol, vol. 18 Suppl C, pp. 53-4.

1994

de Lange, E.C., Danhof, M., de Boer, A.G., Breimer, D.D. , Critical factors of intracerebral microdialysis as a technique to determine the pharmacokinetics of drugs in rat brain, Brain Res, vol. 666, no. 1, pp. 1-8.

Vinks, A.A., Touw, D.J., Heijerman, H.G., Danhof, M., de Leede, G.P., Bakker, W. , Pharmacokinetics of ceftazidime in adult cystic fibrosis patients during continuous infusion and ambulatory treatment at home, Ther Drug Monit, vol. 16, no. 4, pp. 341-8.

1993

Stijnen, A.M., Hovinga, S., Langemeijer, M.W., Hoogerkamp, A., van Bezooijen, C.F., Danhof, M. , Increased sensitivity to the anticonvulsant effect of valproate in aging BN/BiRij rats, Pharm Res, vol. 10, no. 7, pp. 1046-51.

1992

Hovinga, S., Stijnen, A.M., Langemeijer, M.W., Mandema, J.W., van Bezooijen, C.F., Danhof, M. , Pharmacokinetic-EEG effect relationship of midazolam in aging BN/BiRij rats, Br J Pharmacol, vol. 107, no. 1, pp. 171-7.

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