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Universiteit Leiden

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2008

Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78.

Muller, A.E., DeJongh, J., Oostvogel, P.M., Voskuyl, R.A., Dorr, P.J., Danhof, M., Mouton, J.W. , Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6.

2007

Muller, A.E., DeJongh, J., Bult, Y., Goessens, W.H., Mouton, J.W., Danhof, M., van den Anker, J.N. , Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks, Antimicrob Agents Chemother, vol. 51, no. 10, pp. 3720-5.

2006

Swart, E.L., Zuideveld, K.P., de Jongh, J., Danhof, M., Thijs, L.G., van Strack Schijndel, R.M. , Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients, Eur J Clin Pharmacol, vol. 62, no. 3, pp. 185-94.

2005

Groenendaal, D., Blom-Roosemalen, M.C., Danhof, M., Lange, E.C. , High-performance liquid chromatography of nalbuphine, butorphanol and morphine in blood and brain microdialysate samples: application to pharmacokinetic/pharmacodynamic studies in rats, J Chromatogr B Analyt Technol Biomed Life Sci, vol. 822, no. 1-2, pp. 230-7.

2004

Nugroho, A.K., Li, G.L., Danhof, M., Bouwstra, J.A. , Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration, Pharm Res, vol. 21, no. 5, pp. 844-50.

2003

Visser, S.A., Wolters, F.L., Gubbens-Stibbe, J.M., Tukker, E., Van Der Graaf, P.H., Peletier, L.A., Danhof, M. , Mechanism-based pharmacokinetic/pharmacodynamic modeling of the electroencephalogram effects of GABAA receptor modulators: in vitro-in vivo correlations, J Pharmacol Exp Ther, vol. 304, no. 1, pp. 88-101.

2002

Knibbe, C.A., Melenhorst-de Jong, G., Mestrom, M., Rademaker, C.M., Reijnvaan, A.F., Zuideveld, K.P., Kuks, P.F., van Vught, H., Danhof, M. , Pharmacokinetics and effects of propofol 6% for short-term sedation in paediatric patients following cardiac surgery, Br J Clin Pharmacol, vol. 54, no. 4, pp. 415-22.

Li, G.L., van der Geest, R., Chanet, L., van Zanten, E., Danhof, M., Bouwstra, J.A. , In vitro iontophoresis of R-apomorphine across human stratum corneum. Structure-transport relationship of penetration enhancement, J Control Release, vol. 84, no. 1-2, pp. 49-57.

Zuideveld, K.P., Treijtel, N., Maas, H.J., Gubbens-Stibbe, J.M., Peletier, L.A., van Der Graaf, P.H., Danhof, M. , A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia, J Pharmacol Exp Ther, vol. 300, no. 1, pp. 330-8.

2000

Zuideveld, K.P., Treijtel, N., Van der Graaf, P.H., Danhof, M. , Enantioselective high-performance liquid chromatographic analysis of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin. Application to a pharmacokinetic-pharmacodynamic study in rats, J Chromatogr B Biomed Sci Appl, vol. 738, no. 1, pp. 67-73.

Santos, S.R., Papini, O., Omosako, C.E., Pereira, M.D., Quintavalle, T.B., Riccio, M.F., Kurata, A., Pereira, V.A., Di-Pietro, G., Della-Paschoa, O.E., Danhof, M., Da-Luz, P.L. , A simple HPLC-fluorescence method for the measurement of R,S-sotalol in the plasma of patients with life-threatening cardiac arrhythmias, Braz J Med Biol Res, vol. 33, no. 2, pp. 199-204.

Visser, S.A., Smulders, C.J., Gladdines, W.W., Irth, H., van der Graaf, P.H., Danhof, M. , High-performance liquid chromatography of the neuroactive steroids alphaxalone and pregnanolone in plasma using dansyl hydrazine as fluorescent label: application to a pharmacokinetic-pharmacodynamic study in rats, J Chromatogr B Biomed Sci Appl, vol. 745, no. 2, pp. 357-63.

1998

van der Geest, R., van Laar, T., Kruger, P.P., Gubbens-Stibbe, J.M., Bodde, H.E., Roos, R.A., Danhof, M. , Pharmacokinetics, enantiomer interconversion, and metabolism of R-apomorphine in patients with idiopathic Parkinson's disease, Clin Neuropharmacol, vol. 21, no. 3, pp. 159-68.

1997

van Schaick, E.A., de Greef, H.J., Langemeijer, M.W., Sheehan, M.J., AP, I.J., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of the anti-lipolytic and anti-ketotic effects of the adenosine A1-receptor agonist N6-(p-sulphophenyl)adenosine in rats, Br J Pharmacol, vol. 122, no. 3, pp. 525-33.

van der Geest, R., Kruger, P., Gubbens-Stibbe, J.M., van Laar, T., Bodde, H.E., Danhof, M. , Assay of R-apomorphine, S-apomorphine, apocodeine, isoapocodeine and their glucuronide and sulfate conjugates in plasma and urine of patients with Parkinson's disease, J Chromatogr B Biomed Sci Appl, vol. 702, no. 1-2, pp. 131-41.

1995

van Laar, T., Jansen, E.N., Neef, C., Danhof, M., Roos, R.A. , Pharmacokinetics and clinical efficacy of rectal apomorphine in patients with Parkinson's disease: a study of five different suppositories, Mov Disord, vol. 10, no. 4, pp. 433-9.

Mathot, R.A., Cleton, A., Soudijn, W., AP, I.J., Danhof, M. , Pharmacokinetic modelling of the haemodynamic effects of the A2a adenosine receptor agonist CGS 21680C in conscious normotensive rats, Br J Pharmacol, vol. 114, no. 4, pp. 761-8.

1994

Mathot, R.A., Van den Aarsen, B.C., von Frijtag Drabble Kunzel, J.K., Danhof, M., Ijzerman, A.P. , Assessment of the enantiomeric purity of R- and S-N6-phenylisopropyladenosine (PIA): implications for adenosine receptor subclassification, Naunyn Schmiedebergs Arch Pharmacol, vol. 350, no. 1, pp. 109-12.

Irth, H., Cleton, A., Mathot, R.A., Danhof, M., AP, I.J., Tjaden, U.R., van der Greef, J. , Liquid chromatographic determination of the adenosine receptor agonist CGS 21680 in blood using on-line solid-phase extraction on a phenylboronic acid support and fluorescence detection, J Chromatogr B Biomed Appl, vol. 658, no. 1, pp. 207-12.

1993

Mathot, R.A., Appel, S., van Schaick, E.A., Soudijn, W., AP, I.J., Danhof, M. , High-performance liquid chromatography of the adenosine A1 agonist N6-cyclopentyladenosine and the A1 antagonist 8-cyclopentyltheophylline and its application in a pharmacokinetic study in rats, J Chromatogr, vol. 620, no. 1, pp. 113-20.

1992

Stijnen, A.M., Danhof, M., Van Bezooijen, C.F. , Increased sensitivity to the anesthetic effect of phenobarbital in aging BN/BiRij rats, J Pharmacol Exp Ther, vol. 261, no. 1, pp. 81-7.

1991

Mandema, J.W., Gubbens-Stibbe, J.M., Danhof, M. , Stability and pharmacokinetics of flumazenil in the rat, Psychopharmacology (Berl), vol. 103, no. 3, pp. 384-7.

1990

Breimer, L.T., Hennis, P.J., Burm, A.G., Danhof, M., Bovill, J.G., Spierdijk, J., Vletter, A.A. , Quantification of the EEG effect of midazolam by aperiodic analysis in volunteers. Pharmacokinetic/pharmacodynamic modelling, Clin Pharmacokinet, vol. 18, no. 3, pp. 245-53.

1989

van Bree, J.B., de Boer, A.G., Verhoef, J.C., Danhof, M., Breimer, D.D. , Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells, J Pharmacol Exp Ther, vol. 249, no. 3, pp. 901-5.

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