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- 2008
Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model,
J Psychiatr Res, vol. 42, no. 14, pp. 1189-97.
Sensitivity of the individual items of the Hamilton depression rating scale to response and its consequences for the assessment of efficacy,
J Psychiatr Res, vol. 42, no. 12, pp. 1000-9.
The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women,
Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74.
Prediction of attack frequency in migraine treatment,
Cephalalgia, vol. 28, no. 8, pp. 847-55.
Extensions to the visual predictive check to facilitate model performance evaluation,
J Pharmacokinet Pharmacodyn, vol. 35, no. 2, pp. 185-202.
Relevance of absorption rate and lag time to the onset of action in migraine,
Clin Pharmacokinet, vol. 47, no. 2, pp. 139-46.
- 2007
Analysis of responses in migraine modelling using hidden Markov models,
Stat Med, vol. 26, no. 22, pp. 4163-78.
Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments?,
Epilepsia, vol. 48, no. 3, pp. 412-34.
Current issues relating to drug safety especially with regard to the use of biomarkers: a meeting report and progress update,
Eur J Pharm Sci, vol. 30, no. 2, pp. 107-12.
- 2006
A model-based approach to treatment comparison in acute migraine,
Br J Clin Pharmacol, vol. 62, no. 5, pp. 591-600.
A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus,
J Pharmacokinet Pharmacodyn, vol. 33, no. 3, pp. 313-43.
Prediction of headache response in migraine treatment,
Cephalalgia, vol. 26, no. 4, pp. 416-22.
Markers of disease severity in chronic obstructive pulmonary disease,
Pulm Pharmacol Ther, vol. 19, no. 3, pp. 189-99.
- 2005
Disease system analysis: basic disease progression models in degenerative disease,
Pharm Res, vol. 22, no. 7, pp. 1038-49.
Transdermal iontophoretic delivery of apomorphine in patients improved by surfactant formulation pretreatment,
J Control Release, vol. 101, no. 1-3, pp. 199-208.
- 2004
Population pharmacokinetic-pharmacodynamic modelling of the anti-hyperalgesic effect of 5'deoxy-N6-cylopentyladenosine in the mononeuropathic rat,
Eur J Pharmacol, vol. 504, no. 1-2, pp. 7-15.
- 2003
Anticonvulsant drugs differentially suppress individual ictal signs: a pharmacokinetic/pharmacodynamic analysis in the cortical stimulation model in the rat,
Behav Neurosci, vol. 117, no. 5, pp. 1076-85.
Pharmacodynamic analysis of the interaction between tiagabine and midazolam with an allosteric model that incorporates signal transduction,
Epilepsia, vol. 44, no. 3, pp. 329-38.
- 2000
A simple HPLC-fluorescence method for the measurement of R,S-sotalol in the plasma of patients with life-threatening cardiac arrhythmias,
Braz J Med Biol Res, vol. 33, no. 2, pp. 199-204.
- 1998
Effects of repeated seizure induction on seizure activity, post-ictal and interictal behavior,
Brain Res, vol. 814, no. 1-2, pp. 199-208.
- 1994
Pharmacokinetics of ceftazidime in adult cystic fibrosis patients during continuous infusion and ambulatory treatment at home,
Ther Drug Monit, vol. 16, no. 4, pp. 341-8.
- 1992
Properties of the convulsive threshold determined by direct cortical stimulation in rats,
Epilepsy Res, vol. 12, no. 2, pp. 111-20.
- 1989
Pharmacokinetics and hemodynamic effects of long-term nisoldipine treatment in hypertensive patients,
J Cardiovasc Pharmacol, vol. 13, no. 4, pp. 624-9.
- 1978
Therapeutic drug monitoring in saliva,
Clin Pharmacokinet, vol. 3, no. 1, pp. 39-57.



