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Universiteit Leiden

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Filters: keyword is Disease Models [Clear All Filters]

2008

Ravenstijn, P.G., Merlini, M., Hameetman, M., Murray, T.K., Ward, M.A., Lewis, H., Ball, G., Mottart, C., de Ville Goyet, C., Lemarchand, T., van Belle, K., O'Neill, M.J., Danhof, M., de Lange, E.C. , The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments, J Pharmacol Toxicol Methods, vol. 57, no. 2, pp. 114-30.

2007

Jonker, D.M., Voskuyl, R.A., Danhof, M. , Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments?, Epilepsia, vol. 48, no. 3, pp. 412-34.

Liefaard, L.C., Gunput, R.A., Danhof, M., Voskuyl, R.A. , Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy, Epilepsia, vol. 48, no. 7, pp. 1378-87.

Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine, Clin Pharmacokinet, vol. 46, no. 5, pp. 433-47.

2005

Huntjens, D.R., Danhof, M., Della Pasqua, O.E. , Pharmacokinetic-pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors, Rheumatology (Oxford), vol. 44, no. 7, pp. 846-59.

2004

Jonker, D.M., Voskuyl, R.A., Danhof, M. , Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat, Epilepsia, vol. 45, no. 5, pp. 424-35.

2003

Jonker, D.M., van de Mheen, C., Eilers, P.H., Kruk, M.R., Voskuyl, R.A., Danhof, M. , Anticonvulsant drugs differentially suppress individual ictal signs: a pharmacokinetic/pharmacodynamic analysis in the cortical stimulation model in the rat, Behav Neurosci, vol. 117, no. 5, pp. 1076-85.

1999

Cleton, A., Van der Graaf, P.H., Ghijsen, W., Voskuyl, R., Danhof, M. , Mechanism-based modeling of adaptive changes in the pharmacodynamics of midazolam in the kindling model of epilepsy, Pharm Res, vol. 16, no. 11, pp. 1702-9.

1998

Della Paschoa, O.E., Kruk, M.R., Voskuyl, R.A., Danhof, M. , Effects of repeated seizure induction on seizure activity, post-ictal and interictal behavior, Brain Res, vol. 814, no. 1-2, pp. 199-208.

Della Paschoa, O.E., Voskuyl, R.A., Danhof, M. , Modelling of the pharmacodynamic interaction between phenytoin and sodium valproate, Br J Pharmacol, vol. 125, no. 7, pp. 1610-6.

1997

Della Paschoa, O.E., Kruk, M.R., Hamstra, R., Voskuyl, R.A., Danhof, M. , Seizure patterns in kindling and cortical stimulation models of experimental epilepsy, Brain Res, vol. 770, no. 1-2, pp. 221-7.

1995

de Lange, E.C., de Vries, J.D., Zurcher, C., Danhof, M., de Boer, A.G., Breimer, D.D. , The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain, Pharm Res, vol. 12, no. 12, pp. 1924-31.

1993

de Lange, E.C., Danhof, M., de Boer, A.G., Breimer, D.D. , The use of intracerebral microdialysis to study blood-brain barrier transport in health, after modification and in disease, Adv Exp Med Biol, vol. 331, pp. 257-62.

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