LACDR

Universiteit Leiden

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2005

Visser, C.C., Stevanovic, S., Voorwinden, L.H., van Bloois, L., Gaillard, P.J., Danhof, M., Crommelin, D.J., de Boer, A.G. , Targeting liposomes with protein drugs to the blood-brain barrier in vitro, Eur J Pharm Sci, vol. 25, no. 2-3, pp. 299-305.

2004

Visser, C.C., Voorwinden, L.H., Crommelin, D.J., Danhof, M., de Boer, A.G. , Characterization and modulation of the transferrin receptor on brain capillary endothelial cells, Pharm Res, vol. 21, no. 5, pp. 761-9.

Visser, C.C., Stevanovic, S., Heleen Voorwinden, L., Gaillard, P.J., Crommelin, D.J., Danhof, M., De Boer, A.G. , Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro, J Drug Target, vol. 12, no. 3, pp. 145-50.

Visser, C.C., Voorwinden, L.H., Harders, L.R., Eloualid, M., van Bloois, L., Crommelin, D.J., Danhof, M., de Boer, A.G. , Coupling of metal containing homing devices to liposomes via a maleimide linker: use of TCEP to stabilize thiol-groups without scavenging metals, J Drug Target, vol. 12, no. 9-10, pp. 569-73.

2003

Schaddelee, M.P., Voorwinden, H.L., Groenendaal, D., Hersey, A., Ijzerman, A.P., Danhof, M., De Boer, A.G. , Blood-brain barrier transport of synthetic adenosine A1 receptor agonists in vitro: structure transport relationships, Eur J Pharm Sci, vol. 20, no. 3, pp. 347-56.

Schaddelee, M.P., Voorwinden, H.L., van Tilburg, E.W., Pateman, T.J., Ijzerman, A.P., Danhof, M., de Boer, A.G. , Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: possible implications for the design of synthetic adenosine derivatives, Eur J Pharm Sci, vol. 19, no. 1, pp. 13-22.

1997

Bol, C.J., AP, I.J., Danhof, M., Mandema, J.W. , Determination of dexmedetomidine in rat plasma by a sensitive [3H]clonidine radioreceptor assay, J Pharm Sci, vol. 86, no. 7, pp. 822-6.

1989

van Bree, J.B., de Boer, A.G., Verhoef, J.C., Danhof, M., Breimer, D.D. , Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells, J Pharmacol Exp Ther, vol. 249, no. 3, pp. 901-5.

1988

van Bree, J.B., de Boer, A.G., Danhof, M., Ginsel, L.A., Breimer, D.D. , Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs, J Pharmacol Exp Ther, vol. 247, no. 3, pp. 1233-9.

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