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Universiteit Leiden

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2008

Ravenstijn, P.G., Merlini, M., Hameetman, M., Murray, T.K., Ward, M.A., Lewis, H., Ball, G., Mottart, C., de Ville Goyet, C., Lemarchand, T., van Belle, K., O'Neill, M.J., Danhof, M., de Lange, E.C. , The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments, J Pharmacol Toxicol Methods, vol. 57, no. 2, pp. 114-30.

Clinckers, R., Smolders, I, Michotte, Y., Ebinger, G., Danhof, M., Voskuyl, R.A., Della Pasqua, O. , Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain, Br J Pharmacol, vol. 155, no. 7, pp. 1127-38.

2004

Nugroho, A.K., Della Pasqua, O., Danhof, M., Bouwstra, J.A. , Compartmental modeling of transdermal iontophoretic transport: I. In vitro model derivation and application, Pharm Res, vol. 21, no. 11, pp. 1974-84.

2003

Schaddelee, M.P., Voorwinden, H.L., Groenendaal, D., Hersey, A., Ijzerman, A.P., Danhof, M., De Boer, A.G. , Blood-brain barrier transport of synthetic adenosine A1 receptor agonists in vitro: structure transport relationships, Eur J Pharm Sci, vol. 20, no. 3, pp. 347-56.

Schaddelee, M.P., Voorwinden, H.L., van Tilburg, E.W., Pateman, T.J., Ijzerman, A.P., Danhof, M., de Boer, A.G. , Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: possible implications for the design of synthetic adenosine derivatives, Eur J Pharm Sci, vol. 19, no. 1, pp. 13-22.

2002

de Lange, E.C., Danhof, M. , Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain, Clin Pharmacokinet, vol. 41, no. 10, pp. 691-703.

2000

Cleton, A., Odman, J., Van der Graaf, P.H., Ghijsen, W., Voskuyl, R., Danhof, M. , Mechanism-based modeling of functional adaptation upon chronic treatment with midazolam, Pharm Res, vol. 17, no. 3, pp. 321-7.

1992

Van Bree, J.B., De Boer, A.G., Danhof, M., Breimer, D.D. , Drug transport across the blood-brain barrier. II. Experimental techniques to study drug transport, Pharm Weekbl Sci, vol. 14, no. 6, pp. 338-48.

1991

van Bree, J.B., Heijligers-Feijen, C.D., de Boer, A.G., Danhof, M., Breimer, D.D. , Stereoselective transport of baclofen across the blood-brain barrier in rats as determined by the unit impulse response methodology, Pharm Res, vol. 8, no. 2, pp. 259-62.

1989

van Bree, J.B., de Boer, A.G., Verhoef, J.C., Danhof, M., Breimer, D.D. , Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells, J Pharmacol Exp Ther, vol. 249, no. 3, pp. 901-5.

1988

van Bree, J.B., de Boer, A.G., Danhof, M., Ginsel, L.A., Breimer, D.D. , Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs, J Pharmacol Exp Ther, vol. 247, no. 3, pp. 1233-9.

1979

Vonk, R.J., Danhof, M., Coenraads, T., van Doorn, A.B., Keulemans, K., Scaf, A.H., Meijer, D.K. , Influence of bile salts on hepatic transport of dibromosulphthalein, Am J Physiol, vol. 237, no. 6, pp. E524-34.

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