Filters: keyword is Anticonvulsants [Clear All Filters]
- 2008
Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain,
Br J Pharmacol, vol. 155, no. 7, pp. 1127-38.
- 2007
Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments?,
Epilepsia, vol. 48, no. 3, pp. 412-34.
- 2004
Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat,
Epilepsia, vol. 45, no. 5, pp. 424-35.
- 2003
Anticonvulsant drugs differentially suppress individual ictal signs: a pharmacokinetic/pharmacodynamic analysis in the cortical stimulation model in the rat,
Behav Neurosci, vol. 117, no. 5, pp. 1076-85.
Pharmacodynamic analysis of the interaction between tiagabine and midazolam with an allosteric model that incorporates signal transduction,
Epilepsia, vol. 44, no. 3, pp. 329-38.
- 2000
Pharmacokinetic-pharmacodynamic correlation of lamotrigine, flunarizine, loreclezole, CGP40116 and CGP39551 in the cortical stimulation model,
Epilepsy Res, vol. 40, no. 1, pp. 41-52.
Effect of amygdala kindling on the central nervous system effects of tiagabine: EEG effects versus brain GABA levels,
Br J Pharmacol, vol. 130, no. 5, pp. 1037-44.
Pharmacokinetic-pharmacodynamic modelling of tiagabine CNS effects upon chronic treatment in rats: lack of change in concentration-EEG effect relationship,
Eur J Pharm Sci, vol. 12, no. 2, pp. 141-50.
- 1999
Mechanism-based modeling of adaptive changes in the pharmacodynamics of midazolam in the kindling model of epilepsy,
Pharm Res, vol. 16, no. 11, pp. 1702-9.
- 1998
Pharmacodynamic interaction between phenytoin and sodium valproate changes seizure thresholds and pattern,
Br J Pharmacol, vol. 125, no. 5, pp. 997-1004.
Pharmacokinetic-pharmacodynamic modeling of the anticonvulsant and electroencephalogram effects of phenytoin in rats,
J Pharmacol Exp Ther, vol. 284, no. 2, pp. 460-6.
Effects of repeated seizure induction on seizure activity, post-ictal and interictal behavior,
Brain Res, vol. 814, no. 1-2, pp. 199-208.
Modelling of the pharmacodynamic interaction between phenytoin and sodium valproate,
Br J Pharmacol, vol. 125, no. 7, pp. 1610-6.
- 1996
Pharmacokinetic/pharmacodynamic relationship of benzodiazepines in the direct cortical stimulation model of anticonvulsant effect,
J Pharmacol Exp Ther, vol. 279, no. 2, pp. 803-12.
- 1994
Characterization of the pharmacodynamics of several antiepileptic drugs in a direct cortical stimulation model of anticonvulsant effect in the rat,
J Pharmacol Exp Ther, vol. 269, no. 2, pp. 521-8.
- 1993
Increased sensitivity to the anticonvulsant effect of valproate in aging BN/BiRij rats,
Pharm Res, vol. 10, no. 7, pp. 1046-51.
- 1992
Pharmacodynamics of the anticonvulsant effect of oxazepam in aging BN/BiRij rats,
Br J Pharmacol, vol. 107, no. 1, pp. 165-70.
Properties of the convulsive threshold determined by direct cortical stimulation in rats,
Epilepsy Res, vol. 12, no. 2, pp. 111-20.
- 1991
Pharmacokinetic-pharmacodynamic modeling of the electroencephalographic effects of benzodiazepines. Correlation with receptor binding and anticonvulsant activity,
J Pharmacol Exp Ther, vol. 257, no. 1, pp. 472-8.
- 1990
Pharmacodynamics of tolerance development to the anesthetic and anticonvulsant effects of phenobarbital in rats,
J Pharm Sci, vol. 79, no. 3, pp. 207-11.
Pharmacokinetic-pharmacodynamic modelling of the anticonvulsant effect of oxazepam in individual rats,
Br J Pharmacol, vol. 99, no. 1, pp. 53-8.
- 1989
Relationship between receptor occupancy at 37 degrees C and the anticonvulsant effect of flunitrazepam in rats,
Pharm Res, vol. 6, no. 7, pp. 585-91.
- 1988
Pharmacokinetic modeling of the anticonvulsant response of oxazepam in rats using the pentylenetetrazol threshold concentration as pharmacodynamic measure,
J Pharmacokinet Biopharm, vol. 16, no. 2, pp. 203-28.
