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- 2008
Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients,
Clin Pharmacol Ther, vol. 83, no. 3, pp. 443-51.
Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes,
Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6.
The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women,
Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74.
Prediction of attack frequency in migraine treatment,
Cephalalgia, vol. 28, no. 8, pp. 847-55.
- 2007
Application of the convection-dispersion equation to modelling oral drug absorption,
Bull Math Biol, vol. 69, no. 1, pp. 181-95.
Mechanism-based PK/PD modeling of the respiratory depressant effect of buprenorphine and fentanyl in healthy volunteers,
Clin Pharmacol Ther, vol. 81, no. 1, pp. 50-8.
Mechanism-based pharmacokinetic-pharmacodynamic modelling of the reversal of buprenorphine-induced respiratory depression by naloxone : a study in healthy volunteers,
Clin Pharmacokinet, vol. 46, no. 11, pp. 965-80.
- 2006
Buprenorphine induces ceiling in respiratory depression but not in analgesia,
Br J Anaesth, vol. 96, no. 5, pp. 627-32.
Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients,
Eur J Clin Pharmacol, vol. 62, no. 3, pp. 185-94.
A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus,
J Pharmacokinet Pharmacodyn, vol. 33, no. 3, pp. 313-43.
Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers,
Br J Pharmacol, vol. 148, no. 4, pp. 396-404.
Mechanism-based pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine in healthy volunteers,
Anesthesiology, vol. 104, no. 6, pp. 1232-42.
Naloxone reversal of buprenorphine-induced respiratory depression,
Anesthesiology, vol. 105, no. 1, pp. 51-7.
- 2005
Allometric relationships between the pharmacokinetics of propofol in rats, children and adults,
Br J Clin Pharmacol, vol. 59, no. 6, pp. 705-11.
Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats,
Br J Anaesth, vol. 94, no. 6, pp. 825-34.
Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltration,
Am J Kidney Dis, vol. 45, no. 2, pp. 360-71.
Cutaneous side-effects of transdermal iontophoresis with and without surfactant pretreatment: a single-blinded, randomized controlled trial,
Br J Dermatol, vol. 153, no. 2, pp. 404-12.
- 2004
Long-term sedation with propofol 60 mg ml(-1) vs. propofol 10 mg(-1) ml in critically ill, mechanically ventilated patients,
Acta Anaesthesiol Scand, vol. 48, no. 3, pp. 302-7.
Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients,
Br J Clin Pharmacol, vol. 57, no. 2, pp. 135-45.
Transdermal iontophoresis of rotigotine: influence of concentration, temperature and current density in human skin in vitro,
J Control Release, vol. 96, no. 1, pp. 159-67.
- 2002
Pharmacokinetics and effects of propofol 6% for short-term sedation in paediatric patients following cardiac surgery,
Br J Clin Pharmacol, vol. 54, no. 4, pp. 415-22.
Correlation between midazolam and lignocaine pharmacokinetics and MEGX formation in healthy volunteers,
Br J Clin Pharmacol, vol. 53, no. 2, pp. 133-9.
Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%,
Clin Pharmacol Ther, vol. 72, no. 6, pp. 670-84.
- 2000
A pharmacodynamic Markov mixed-effects model for the effect of temazepam on sleep,
Clin Pharmacol Ther, vol. 68, no. 2, pp. 175-88.
Pharmacokinetics and pharmacodynamics of propofol 6% SAZN versus propofol 1% SAZN and Diprivan-10 for short-term sedation following coronary artery bypass surgery,
Eur J Clin Pharmacol, vol. 56, no. 1, pp. 89-95.



