LACDR

Universiteit Leiden

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Filters: keyword is Adrenergic beta-Antagonists [Clear All Filters]

2008

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther, vol. 324, no. 3, pp. 1234-42.

2007

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint, Br J Pharmacol, vol. 151, no. 3, pp. 356-66.

van Steeg, T.J., Krekels, E.H., Danhof, M., de Lange, E.C. , Reproducible and time-dependent modification of serum protein binding in Wistar Kyoto rats, J Pharmacol Toxicol Methods, vol. 56, no. 1, pp. 72-8.

1995

de Lange, E.C., Bouw, M.R., Mandema, J.W., Danhof, M., de Boer, A.G., Breimer, D.D. , Application of intracerebral microdialysis to study regional distribution kinetics of drugs in rat brain, Br J Pharmacol, vol. 116, no. 5, pp. 2538-44.

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