LACDR

Universiteit Leiden

List
Filter

Found 7 results. Export: Tagged | XML

Filters: keyword is Adrenergic [Clear All Filters]

2008

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther, vol. 324, no. 3, pp. 1234-42.

2007

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint, Br J Pharmacol, vol. 151, no. 3, pp. 356-66.

van Steeg, T.J., Krekels, E.H., Danhof, M., de Lange, E.C. , Reproducible and time-dependent modification of serum protein binding in Wistar Kyoto rats, J Pharmacol Toxicol Methods, vol. 56, no. 1, pp. 72-8.

1997

Van der Graaf, P.H., Danhof, M. , On the reliability of affinity and efficacy estimates obtained by direct operational model fitting of agonist concentration-effect curves following irreversible receptor inactivation, J Pharmacol Toxicol Methods, vol. 38, no. 2, pp. 81-5.

Bol, C.J., AP, I.J., Danhof, M., Mandema, J.W. , Determination of dexmedetomidine in rat plasma by a sensitive [3H]clonidine radioreceptor assay, J Pharm Sci, vol. 86, no. 7, pp. 822-6.

Bol, C., Danhof, M., Stanski, D.R., Mandema, J.W. , Pharmacokinetic-pharmacodynamic characterization of the cardiovascular, hypnotic, EEG and ventilatory responses to dexmedetomidine in the rat, J Pharmacol Exp Ther, vol. 283, no. 3, pp. 1051-8.

1995

de Lange, E.C., Bouw, M.R., Mandema, J.W., Danhof, M., de Boer, A.G., Breimer, D.D. , Application of intracerebral microdialysis to study regional distribution kinetics of drugs in rat brain, Br J Pharmacol, vol. 116, no. 5, pp. 2538-44.

LACDR