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Universiteit Leiden

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1993

Van Bree, J.B., De Boer, A.G., Danhof, M., Breimer, D.D. , Drug transport across the blood-brain barrier. III. Mechanisms and methods to improve drug delivery to the central nervous system, Pharm World Sci, vol. 15, no. 1, pp. 2-9.

1992

Van Bree, J.B., De Boer, A.G., Danhof, M., Breimer, D.D. , Drug transport across the blood--brain barrier. I. Anatomical and physiological aspects, Pharm Weekbl Sci, vol. 14, no. 5, pp. 305-10.

Van Bree, J.B., De Boer, A.G., Danhof, M., Breimer, D.D. , Drug transport across the blood-brain barrier. II. Experimental techniques to study drug transport, Pharm Weekbl Sci, vol. 14, no. 6, pp. 338-48.

1991

van Bree, J.B., Heijligers-Feijen, C.D., de Boer, A.G., Danhof, M., Breimer, D.D. , Stereoselective transport of baclofen across the blood-brain barrier in rats as determined by the unit impulse response methodology, Pharm Res, vol. 8, no. 2, pp. 259-62.

1990

van Bree, J.B., Tio, S., de Boer, A.G., Danhof, M., Verhoef, J.C., Breimer, D.D. , Transport of desglycinamide-arginine vasopressin across the blood-brain barrier in rats as evaluated by the unit impulse response methodology, Pharm Res, vol. 7, no. 3, pp. 293-8.

1989

Dingemanse, J., van Bree, J.B., Danhof, M. , Pharmacokinetic modeling of the anticonvulsant action of phenobarbital in rats, J Pharmacol Exp Ther, vol. 249, no. 2, pp. 601-8.

van Bree, J.B., de Boer, A.G., Verhoef, J.C., Danhof, M., Breimer, D.D. , Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells, J Pharmacol Exp Ther, vol. 249, no. 3, pp. 901-5.

van Bree, J.B., Baljet, A.V., van Geyt, A., de Boer, A.G., Danhof, M., Breimer, D.D. , The unit impulse response procedure for the pharmacokinetic evaluation of drug entry into the central nervous system, J Pharmacokinet Biopharm, vol. 17, no. 4, pp. 441-62.

1988

van Bree, J.B., de Boer, A.G., Danhof, M., Verhoef, J.C., van Wimersma Greidanus, T.B., Breimer, D.D. , Radioimmunoassay of desglycinamide-arginine vasopressin and its application in a pharmacokinetic study in the rat, Peptides, vol. 9, no. 3, pp. 555-9.

van Bree, J.B., de Boer, A.G., Danhof, M., Ginsel, L.A., Breimer, D.D. , Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs, J Pharmacol Exp Ther, vol. 247, no. 3, pp. 1233-9.

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