LACDR

Universiteit Leiden

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2008

Groenendaal, D., Freijer, J., Rosier, A., de Mik, D., Nicholls, G., Hersey, A., Ayrton, A.D., Danhof, M., de Lange, E.C. , Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci, vol. 34, no. 2-3, pp. 149-63.

2007

Groenendaal, D., Freijer, J., de Mik, D., Bouw, M.R., Danhof, M., de Lange, E.C. , Influence of biophase distribution and P-glycoprotein interaction on pharmacokinetic-pharmacodynamic modelling of the effects of morphine on the EEG, Br J Pharmacol, vol. 151, no. 5, pp. 713-20.

Groenendaal, D., Freijer, J., de Mik, D., Bouw, M.R., Danhof, M., de Lange, E.C. , Population pharmacokinetic modelling of non-linear brain distribution of morphine: influence of active saturable influx and P-glycoprotein mediated efflux, Br J Pharmacol, vol. 151, no. 5, pp. 701-12.

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