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- 2005
Targeting liposomes with protein drugs to the blood-brain barrier in vitro,
Eur J Pharm Sci, vol. 25, no. 2-3, pp. 299-305.
Towards a mechanism-based analysis of pharmacodynamic drug-drug interactions in vivo,
Pharmacol Ther, vol. 106, no. 1, pp. 1-18.
- 2004
Characterization and modulation of the transferrin receptor on brain capillary endothelial cells,
Pharm Res, vol. 21, no. 5, pp. 761-9.
Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro,
J Drug Target, vol. 12, no. 3, pp. 145-50.
Coupling of metal containing homing devices to liposomes via a maleimide linker: use of TCEP to stabilize thiol-groups without scavenging metals,
J Drug Target, vol. 12, no. 9-10, pp. 569-73.
- 2003
Mechanism-based modeling of the pharmacodynamic interaction of alphaxalone and midazolam in rats,
J Pharmacol Exp Ther, vol. 307, no. 2, pp. 765-75.
Dose-dependent EEG effects of zolpidem provide evidence for GABA(A) receptor subtype selectivity in vivo,
J Pharmacol Exp Ther, vol. 304, no. 3, pp. 1251-7.
Mechanism-based pharmacokinetic/pharmacodynamic modeling of the electroencephalogram effects of GABAA receptor modulators: in vitro-in vivo correlations,
J Pharmacol Exp Ther, vol. 304, no. 1, pp. 88-101.
- 2002
Mechanism-based pharmacokinetic-pharmacodynamic modeling of concentration-dependent hysteresis and biphasic electroencephalogram effects of alphaxalone in rats,
J Pharmacol Exp Ther, vol. 302, no. 3, pp. 1158-67.
Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo,
J Pharmacol Exp Ther, vol. 303, no. 2, pp. 616-26.
Pharmaco-electroencephalography and pharmacokinetic-pharmacodynamic modeling in drug development: focus on preclinical steps,
Methods Find Exp Clin Pharmacol, vol. 24 Suppl D, pp. 127-8.
- 2000
High-performance liquid chromatography of the neuroactive steroids alphaxalone and pregnanolone in plasma using dansyl hydrazine as fluorescent label: application to a pharmacokinetic-pharmacodynamic study in rats,
J Chromatogr B Biomed Sci Appl, vol. 745, no. 2, pp. 357-63.
- 1999
Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: prediction of tissue-dependent efficacy in vivo,
J Pharmacol Exp Ther, vol. 290, no. 2, pp. 702-9.



