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Universiteit Leiden

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2009

Ince, I, de Wildt, S.N., Tibboel, D., Danhof, M., Knibbe, C.A. , Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling, Drug Discov Today, vol. 14, no. 5-6, pp. 316-20.

2008

Peeters, M.Y., Bras, L.J., DeJongh, J., Wesselink, R.M., Aarts, L.P., Danhof, M., Knibbe, C.A. , Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients, Clin Pharmacol Ther, vol. 83, no. 3, pp. 443-51.

Peeters, M.Y., Aarts, L.P., Boom, F.A., Bras, L.J., Tibboel, D., Danhof, M., Knibbe, C.A. , Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients, Eur J Clin Pharmacol, vol. 64, no. 3, pp. 329-34.

2006

Peeters, M.Y., Prins, S.A., Knibbe, C.A., DeJongh, J., van Schaik, R.H., van Dijk, M., van der Heiden, I.P., Tibboel, D., Danhof, M. , Propofol pharmacokinetics and pharmacodynamics for depth of sedation in nonventilated infants after major craniofacial surgery, Anesthesiology, vol. 104, no. 3, pp. 466-74.

Peeters, M.Y., Prins, S.A., Knibbe, C.A., Dejongh, J., Mathot, R.A., Warris, C., van Schaik, R.H., Tibboel, D., Danhof, M. , Pharmacokinetics and pharmacodynamics of midazolam and metabolites in nonventilated infants after craniofacial surgery, Anesthesiology, vol. 105, no. 6, pp. 1135-46.

2005

Prins, S.A., Peeters, M.Y., Houmes, R.J., van Dijk, M., Knibbe, C.A., Danhof, M., Tibboel, D. , Propofol 6% as sedative in children under 2 years of age following major craniofacial surgery, Br J Anaesth, vol. 94, no. 5, pp. 630-5.

Knibbe, C.A., Zuideveld, K.P., Aarts, L.P., Kuks, P.F., Danhof, M. , Allometric relationships between the pharmacokinetics of propofol in rats, children and adults, Br J Clin Pharmacol, vol. 59, no. 6, pp. 705-11.

2004

Knibbe, C.A., Naber, H., Aarts, L.P., Kuks, P.F., Danhof, M. , Long-term sedation with propofol 60 mg ml(-1) vs. propofol 10 mg(-1) ml in critically ill, mechanically ventilated patients, Acta Anaesthesiol Scand, vol. 48, no. 3, pp. 302-7.

2002

Knibbe, C.A., Melenhorst-de Jong, G., Mestrom, M., Rademaker, C.M., Reijnvaan, A.F., Zuideveld, K.P., Kuks, P.F., van Vught, H., Danhof, M. , Pharmacokinetics and effects of propofol 6% for short-term sedation in paediatric patients following cardiac surgery, Br J Clin Pharmacol, vol. 54, no. 4, pp. 415-22.

Knibbe, C.A., Zuideveld, K.P., DeJongh, J., Kuks, P.F., Aarts, L.P., Danhof, M. , Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%, Clin Pharmacol Ther, vol. 72, no. 6, pp. 670-84.

2000

Knibbe, C.A., Aarts, L.P., Kuks, P.F., Voortman, H.J., Lie, A.H.L., Bras, L.J., Danhof, M. , Pharmacokinetics and pharmacodynamics of propofol 6% SAZN versus propofol 1% SAZN and Diprivan-10 for short-term sedation following coronary artery bypass surgery, Eur J Clin Pharmacol, vol. 56, no. 1, pp. 89-95.

1999

Knibbe, C.A., Koster, V.S., Aarts, L.P., Langemeijer, H.J., Danhof, M. , Pilot study in humans on the pharmacokinetics and safety of propofol 6% SAZN, Pharm World Sci, vol. 21, no. 5, pp. 239-40.

Knibbe, C.A., Voortman, H.J., Aarts, L.P., Kuks, P.F., Lange, R., Langemeijer, H.J., Danhof, M. , Pharmacokinetics, induction of anaesthesia and safety characteristics of propofol 6% SAZN vs propofol 1% SAZN and Diprivan-10 after bolus injection, Br J Clin Pharmacol, vol. 47, no. 6, pp. 653-60.

1998

Cox, E.H., Knibbe, C.A., Koster, V.S., Langemeijer, M.W., Tukker, E.E., Lange, R., Kuks, P.F., Langemeijer, H.J., Lie, A.H.L., Danhof, M. , Influence of different fat emulsion-based intravenous formulations on the pharmacokinetics and pharmacodynamics of propofol, Pharm Res, vol. 15, no. 3, pp. 442-8.

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