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Universiteit Leiden

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2003

Visser, S.A., Wolters, F.L., Gubbens-Stibbe, J.M., Tukker, E., Van Der Graaf, P.H., Peletier, L.A., Danhof, M. , Mechanism-based pharmacokinetic/pharmacodynamic modeling of the electroencephalogram effects of GABAA receptor modulators: in vitro-in vivo correlations, J Pharmacol Exp Ther, vol. 304, no. 1, pp. 88-101.

2002

Zuideveld, K.P., Treijtel, N., Maas, H.J., Gubbens-Stibbe, J.M., Peletier, L.A., van Der Graaf, P.H., Danhof, M. , A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia, J Pharmacol Exp Ther, vol. 300, no. 1, pp. 330-8.

2000

Garrido, M., Gubbens-Stibbe, J., Tukker, E., Cox, E., von Frijtag, J., Kunzel, D., A, I.J., Danhof, M., van der Graaf, P.H. , Pharmacokinetic-pharmacodynamic analysis of the EEG effect of alfentanil in rats following beta-funaltrexamine-induced mu-opioid receptor "knockdown" in vivo, Pharm Res, vol. 17, no. 6, pp. 653-9.

1999

Cox, E.H., Langemeijer, M.W., Gubbens-Stibbe, J.M., Muir, K.T., Danhof, M. , The comparative pharmacodynamics of remifentanil and its metabolite, GR90291, in a rat electroencephalographic model, Anesthesiology, vol. 90, no. 2, pp. 535-44.

1998

van der Geest, R., van Laar, T., Kruger, P.P., Gubbens-Stibbe, J.M., Bodde, H.E., Roos, R.A., Danhof, M. , Pharmacokinetics, enantiomer interconversion, and metabolism of R-apomorphine in patients with idiopathic Parkinson's disease, Clin Neuropharmacol, vol. 21, no. 3, pp. 159-68.

1997

van der Geest, R., Kruger, P., Gubbens-Stibbe, J.M., van Laar, T., Bodde, H.E., Danhof, M. , Assay of R-apomorphine, S-apomorphine, apocodeine, isoapocodeine and their glucuronide and sulfate conjugates in plasma and urine of patients with Parkinson's disease, J Chromatogr B Biomed Sci Appl, vol. 702, no. 1-2, pp. 131-41.

Van Schaick, E.A., Math-ot, R.A., Gubbens-Stibbe, J.M., Langemeijer, M.W., Roelen, H.C., Ijzerman, A.P., Danhof, M. , 8-Alkylamino-substituted analogs of N6-cyclopentyladenosine are partial agonists for the cardiovascular adenosine A1 receptors in vivo, J Pharmacol Exp Ther, vol. 283, no. 2, pp. 800-8.

van der Geest, R., van Laar, T., Gubbens-Stibbe, J.M., Bodde, H.E., Danhof, M. , Iontophoretic delivery of apomorphine. II: An in vivo study in patients with Parkinson's disease, Pharm Res, vol. 14, no. 12, pp. 1804-10.

1995

Mathot, R.A., Gubbens-Stibbe, J.M., Soudijn, W., Jacobson, K.A., Ijzerman, A.P., Danhof, M. , Quantification of the in vivo potency of the adenosine A2 receptor antagonist 8-(3-chlorostyryl)caffeine, J Pharmacol Exp Ther, vol. 275, no. 1, pp. 245-53.

1991

Mandema, J.W., Gubbens-Stibbe, J.M., Danhof, M. , Stability and pharmacokinetics of flumazenil in the rat, Psychopharmacology (Berl), vol. 103, no. 3, pp. 384-7.

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