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- 2008
Pharmacokinetic-pharmacodynamic modeling of the effectiveness and safety of buprenorphine and fentanyl in rats,
Pharm Res, vol. 25, no. 1, pp. 183-93.
- 2007
Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of norbuprenorphine in rats,
J Pharmacol Exp Ther, vol. 321, no. 2, pp. 598-607.
Mechanism-based PK/PD modeling of the respiratory depressant effect of buprenorphine and fentanyl in healthy volunteers,
Clin Pharmacol Ther, vol. 81, no. 1, pp. 50-8.
Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine,
Clin Pharmacokinet, vol. 46, no. 5, pp. 433-47.
Mechanism-based pharmacokinetic-pharmacodynamic modelling of the reversal of buprenorphine-induced respiratory depression by naloxone : a study in healthy volunteers,
Clin Pharmacokinet, vol. 46, no. 11, pp. 965-80.
- 2006
Mechanism-based pharmacokinetic-pharmacodynamic modeling of the respiratory-depressant effect of buprenorphine and fentanyl in rats,
J Pharmacol Exp Ther, vol. 319, no. 2, pp. 682-92.
Buprenorphine induces ceiling in respiratory depression but not in analgesia,
Br J Anaesth, vol. 96, no. 5, pp. 627-32.
Mechanism-based pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine in healthy volunteers,
Anesthesiology, vol. 104, no. 6, pp. 1232-42.
Naloxone reversal of buprenorphine-induced respiratory depression,
Anesthesiology, vol. 105, no. 1, pp. 51-7.
- 2005
Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats,
Br J Anaesth, vol. 94, no. 6, pp. 825-34.
Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine and fentanyl in rats: role of receptor equilibration kinetics,
J Pharmacol Exp Ther, vol. 313, no. 3, pp. 1136-49.
