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Universiteit Leiden

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2009

Huntjens, D.R., Spalding, D.J., Danhof, M., Della Pasqua, O.E. , Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors, Eur J Pain, vol. 13, no. 5, pp. 448-57.

Maas, H., Danhof, M., Della Pasqua, O. , Analysis of the relationship between age and treatment response in migraine, Cephalalgia.

Ince, I, de Wildt, S.N., Tibboel, D., Danhof, M., Knibbe, C.A. , Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling, Drug Discov Today, vol. 14, no. 5-6, pp. 316-20.

Verpoorte, R., Crommelin, D., Danhof, M., Gilissen, L.J., Schuitmaker, H., van der Greef, J., Witkamp, R.F. , Commentary: "A systems view on the future of medicine: inspiration from Chinese medicine?", J Ethnopharmacol, vol. 121, no. 3, pp. 479-81.

Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., de Jong, H.W., Dijkstra, J., van der Weerd, L., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Changes in GABAA receptor properties in amygdala kindled animals: in vivo studies using [11C]flumazenil and positron emission tomography, Epilepsia, vol. 50, no. 1, pp. 88-98.

Ploeger, B.A., Smeets, J., Strougo, A., Drenth, H.J., Ruigt, G., Houwing, N., Danhof, M. , Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex, Anesthesiology, vol. 110, no. 1, pp. 95-105.

Santen, G., Danhof, M., Pasqua, O.D. , Sensitivity of the Montgomery Asberg Depression Rating Scale to response and its consequences for the assessment of efficacy, J Psychiatr Res.

Press, R.R., Ploeger, B.A., den Hartigh, J., van der Straaten, T., van Pelt, J., Danhof, M., de Fijter, J.W., Guchelaar, H.J. , Explaining variability in tacrolimus pharmacokinetics to optimize early exposure in adult kidney transplant recipients, Ther Drug Monit, vol. 31, no. 2, pp. 187-97.

Muller, A.E., Oostvogel, P.M., DeJongh, J., Mouton, J.W., Steegers, E.A., Dorr, P.J., Danhof, M., Voskuyl, R.A. , Pharmacokinetics of amoxicillin in maternal, umbilical cord, and neonatal sera, Antimicrob Agents Chemother, vol. 53, no. 4, pp. 1574-80.

Ploeger, B.A., Graaf, P.H., Danhof, M. , Incorporating receptor theory in mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling, Drug Metab Pharmacokinet, vol. 24, no. 1, pp. 3-15.

2008

Santen, G., Danhof, M., Della Pasqua, O. , Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model, J Psychiatr Res, vol. 42, no. 14, pp. 1189-97.

Santen, G., Gomeni, R., Danhof, M., Della Pasqua, O. , Sensitivity of the individual items of the Hamilton depression rating scale to response and its consequences for the assessment of efficacy, J Psychiatr Res, vol. 42, no. 12, pp. 1000-9.

Ravenstijn, P.G., Merlini, M., Hameetman, M., Murray, T.K., Ward, M.A., Lewis, H., Ball, G., Mottart, C., de Ville Goyet, C., Lemarchand, T., van Belle, K., O'Neill, M.J., Danhof, M., de Lange, E.C. , The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments, J Pharmacol Toxicol Methods, vol. 57, no. 2, pp. 114-30.

Geldof, M., Freijer, J. I, Peletier, L.A., van Beijsterveldt, L., Danhof, M. , Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex, Eur J Pharm Sci, vol. 33, no. 3, pp. 217-29.

Peeters, M.Y., Bras, L.J., DeJongh, J., Wesselink, R.M., Aarts, L.P., Danhof, M., Knibbe, C.A. , Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients, Clin Pharmacol Ther, vol. 83, no. 3, pp. 443-51.

van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther, vol. 324, no. 3, pp. 1234-42.

Huntjens, D.R., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D.J., Danhof, M., Della Pasqua, O. , Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats, Br J Pharmacol, vol. 153, no. 5, pp. 1072-84.

Peeters, M.Y., Aarts, L.P., Boom, F.A., Bras, L.J., Tibboel, D., Danhof, M., Knibbe, C.A. , Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients, Eur J Clin Pharmacol, vol. 64, no. 3, pp. 329-34.

Groenendaal, D., Freijer, J., Rosier, A., de Mik, D., Nicholls, G., Hersey, A., Ayrton, A.D., Danhof, M., de Lange, E.C. , Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci, vol. 34, no. 2-3, pp. 149-63.

Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78.

Muller, A.E., DeJongh, J., Oostvogel, P.M., Voskuyl, R.A., Dorr, P.J., Danhof, M., Mouton, J.W. , Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6.

Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effectiveness and safety of buprenorphine and fentanyl in rats, Pharm Res, vol. 25, no. 1, pp. 183-93.

van Steeg, T.J., Boralli, V.B., Krekels, E.H., Slijkerman, P., Freijer, J., Danhof, M., de Lange, E.C. , Influence of plasma protein binding on pharmacodynamics: Estimation of in vivo receptor affinities of beta blockers using a new mechanism-based PK-PD modelling approach, J Pharm Sci.

Clinckers, R., Smolders, I, Michotte, Y., Ebinger, G., Danhof, M., Voskuyl, R.A., Della Pasqua, O. , Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain, Br J Pharmacol, vol. 155, no. 7, pp. 1127-38.

Muller, A.E., Dorr, P.J., Mouton, J.W., De Jongh, J., Oostvogel, P.M., Steegers, E.A., Voskuyl, R.A., Danhof, M. , The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women, Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74.

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