Pilot study in humans on the pharmacokinetics and safety of propofol 6% SAZN

Publication Type:

Journal Article

Authors:

Knibbe, C.A.; Koster, V.S.; Aarts, L.P.; Langemeijer, H.J.; Danhof, M.

Source:

Pharm World Sci, Volume 21, Number 5, p.239-40 (1999)

ISBN:

0928-1231 (Print)

Keywords:

Adult; Anesthetics; Intravenous/adverse effects/pharmacokinetics; Double-Blind Method; Female; Humans; Middle Aged; Pilot Projects; Propofol/*adverse effects/blood/*pharmacokinetics; Time Factors

Abstract:

In a pilot study on the first application of Propofol 6% SAZN in humans, the pharmacokinetics and safety of the new product seem to be similar to those of Propofol 1% SAZN and Diprivan-10 after bolus injection. The results will have to be confirmed in a larger clinical study in order to develop Propofol 6% SAZN as an alternative for Diprivan-10.

27/04/2009